Dow Jones
52,377.57
Change
+15.99+0.03%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are broadly higher today, with the Dow Jones up 0.03%, the S&P 500 up 0.60%, and the Nasdaq Composite up 1.18%. Market breadth is also positive, with 2,686 stocks advancing versus 2,432 declining, indicating a broadly bullish bias.
S&P 500
7,722.6
Change
+45.83+0.60%
Nasdaq Composite
26,477.811
Change
+308.43+1.18%
24H Gainers
2,686
24H Losers
2,432
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 1 | Eloxx Pharmaceuticals, Inc.ELOX | $13.34 | -1.52% | 10.16K | $53.83M | $12.55 - $23.40 | 0.00% |
| 2 | Mega Fortune Company LimitedMGRT | $117.00 | -2.50% | 3.30K | $1.61B | $4.04 - $170.00 | 0.00% |
| 3 | Bank of New York Mellon CorporationBNY | $147.59 | +0.27% | 1.30M | $100.14B | $10.05 - $165.84 | 0.02% |
| 4 | TJGC Group LimitedTJGC | $31.64 | -3.18% | 68.09K | $319.51M | $1.46 - $36.76 | 0.00% |
| 5 | Nine Energy Service, Inc.NINE | $7.85 | -1.26% | 11.33K | $107.41M | $0.29 - $13.23 | 0.00% |
| 6 | AXT Inc.AXTI | $58.20 | +4.48% | 8.47M | $3.82B | $5.86 - $143.16 | 0.00% |
| 7 | BUUU Group LimitedBUUU | $6.70 | +0.16% | 2.01M | $7.73B | $0.57 - $7.31 | 0.00% |
| 8 | Moderna, Inc.MRNA | $207.86 | +4.53% | 16.88M | $82.98B | $22.28 - $254.48 | 0.00% |
| 9 | Sandisk CorporationSNDK | $1,304.76 | +3.93% | 6.35M | $178.93B | $164.56 - $2,354.39 | 0.00% |
| 10 | MMTec, Inc.MTC | $5.45 | -4.27% | 7.25K | $542.26M | $0.25 - $9.10 | 0.00% |
| 11 | Erasca, Inc.ERAS | $15.22 | +1.53% | 4.12M | $5.32B | $2.10 - $24.28 | 0.00% |
| 12 | Iovance Biotherapeutics, Inc.IOVA | $14.57 | +5.77% | 7.86M | $6.60B | $1.76 - $15.37 | 0.00% |
| 13 | SELLAS Life Sciences Group, Inc.SLS | $12.16 | +7.14% | 5.70M | $2.46B | $1.39 - $15.88 | 0.00% |
| 14 | 10x Genomics, Inc.TXG | $78.06 | +6.92% | 1.72M | $9.38B | $12.34 - $102.81 | 0.00% |
| 15 | Space Exploration Technologies Corp.SPCX | $148.60 | +1.36% | 85.32M | $2.00T | $21.32 - $225.64 | 0.00% |
| 16 | CareDx, Inc.CDNA | $70.56 | +2.10% | 975.35K | $3.65B | $14.22 - $72.71 | 0.00% |
| 17 | Kodiak Sciences Inc.KOD | $91.35 | +2.04% | 859.40K | $5.74B | $15.83 - $104.00 | 0.00% |
| 18 | MaxLinear, Inc.MXL | $74.61 | +12.37% | 3.37M | $6.79B | $12.77 - $128.30 | 0.00% |
| 19 | Twist Bioscience CorporationTWST | $159.84 | +10.06% | 1.57M | $10.02B | $23.30 - $219.71 | 0.00% |
| 20 | Climb Bio, Inc.CLYM | $9.57 | +8.63% | 3.72M | $549.44M | $1.64 - $18.33 | 0.00% |
| 21 | Lumentum Holdings Inc.LITE | $866.12 | +5.40% | 5.14M | $78.46B | $184.20 - $1,143.00 | 0.00% |
| 22 | Avita Medical, Inc.RCEL | $16.04 | +5.96% | 525.62K | $493.69M | $3.22 - $16.13 | 0.00% |
| 23 | Micron Technology, Inc.MU | $928.86 | +2.39% | 16.15M | $1.05T | $192.59 - $1,255.00 | 0.00% |
| 24 | Anterix Inc.ATEX | $85.70 | +7.85% | 175.75K | $1.68B | $17.58 - $113.00 | 0.00% |
| 25 | WISeSat.Space Holdings Corp.SAIQ | $7.47 | +10.25% | 4.69M | $102.93M | $1.76 - $9.94 | 0.00% |
| 26 | New Century Logistics (BVI) LimitedNCEW | $16.85 | +0.37% | 12 | $53.92M | $2.80 - $20.83 | 0.00% |
| 27 | Spyre Therapeutics, Inc.SYRE | $99.05 | +6.62% | 816.17K | $10.09B | $21.14 - $110.17 | 0.00% |
| 28 | agilon health, inc.AGL | $90.54 | +0.34% | 89.69K | $1.52B | $7.48 - $133.04 | 0.00% |
| 29 | PACS Group, Inc.PACS | $47.84 | -1.76% | 599.20K | $7.57B | $10.31 - $49.78 | 0.00% |
| 30 | Vince Holding Corp.VNCE | $11.18 | -2.19% | 209.31K | $144.71M | $1.95 - $13.78 | 0.00% |
| 31 | EuroDry LtdEDRY | $45.73 | +0.93% | 70.92K | $131.08M | $12.08 - $73.07 | 0.00% |
| 32 | Veradermics, IncorporatedMANE | $140.59 | +2.42% | 404.12K | $5.80B | $32.00 - $141.75 | 0.00% |
| 33 | Ampco-Pittsburgh Corp.AP | $8.31 | +8.09% | 79.44K | $171.76M | $1.75 - $12.81 | 0.00% |
| 34 | Alto Ingredients, Inc.ALTO | $3.71 | +1.50% | 948.73K | $288.16M | $0.99 - $6.11 | 0.00% |
| 35 | SAIHEAT LimitedSAIH | $27.86 | -5.19% | 18.63K | $33.31M | $5.90 - $33.00 | 0.00% |
| 36 | Oruka Therapeutics, Inc.ORKA | $95.81 | +6.12% | 1.07M | $6.34B | $25.23 - $115.52 | 0.00% |
| 37 | Agencia Comercial Spirits LtdAGCC | $14.81 | +0.85% | 6.34K | $646.08M | $4.23 - $25.73 | 0.00% |
| 38 | QTREX Quantum Ltd.QTEX | $1.33 | +3.10% | 5.27M | $74.71M | $0.28 - $3.85 | 0.00% |
| 39 | Butterfly Network, Inc.BFLY | $7.39 | +11.41% | 4.30M | $1.81B | $1.90 - $10.21 | 0.00% |
| 40 | Biodesix, Inc.BDSX | $21.90 | +2.45% | 137.69K | $231.06M | $5.26 - $31.97 | 0.00% |
| 41 | Fastly, Inc.FSLY | $27.37 | +6.87% | 4.60M | $4.36B | $7.87 - $34.82 | 0.00% |
| 42 | Alpha Tau Medical Ltd.DRTS | $13.51 | +4.81% | 303.53K | $1.22B | $3.43 - $15.79 | 0.00% |
| 43 | ImmunityBio, Inc.IBRX | $8.63 | +10.50% | 9.41M | $9.14B | $1.95 - $12.43 | 0.00% |
| 44 | Revolution Medicines, Inc.RVMD | $186.28 | +1.28% | 949.39K | $39.93B | $55.40 - $224.31 | 0.00% |
| 45 | Rallybio CorporationRLYB | $15.99 | -2.83% | 52.16K | $84.97M | $3.67 - $17.57 | 0.00% |
| 46 | Maase Inc.MAAS | $12.11 | +0.83% | 26.27K | $112.02M | $3.51 - $24.90 | 0.00% |
| 47 | Entravision CommunicationEVC | $6.29 | +2.61% | 710.50K | $522.08M | $1.98 - $13.74 | 0.03% |
| 48 | Q32 Bio Inc.QTTB | $8.74 | +3.31% | 574.04K | $260.10M | $1.91 - $23.57 | 0.00% |
| 49 | OmniAb, Inc.OABI | $4.95 | +7.38% | 848.46K | $718.19M | $1.30 - $5.43 | 0.00% |
| 50 | Dell Technologies Inc.DELL | $501.70 | +7.36% | 5.53M | $158.25B | $110.22 - $595.51 | 0.01% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Eloxx Pharmaceuticals, Inc. (ELOX) currently leads with a 52-week gain of 1,179,627.27% as of 2026-10-28 02:46 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
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Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.