Spyre Therapeutics, Inc. (SYRE)

NASDAQ

$92.97

$+1.50

(+1.64%)

After-Hours

Spyre Therapeutics, Inc. (SYRE) Live Price Chart

Last updated: ⁦2026-10-21 22:26:20⁩. Prices reflect the latest after-hours trading data. Stock price data is sourced from Massive.

Summary

Spyre Therapeutics, Inc. (SYRE) operates in the PHARMACEUTICAL PREPARATIONS sector and is listed on NASDAQ. The stock is currently priced at $92.97, with a market capitalization of $7.92B and a P/E ratio of --. Over the past 52 weeks, its price has ranged from $21.15 to $110.18. This page covers its latest market performance, valuation, price trends and company information.

Key Market Data

Market Cap	$7.92B
Open	$92.78
Day's High	$110.18
Day's Low	$10.42
Previous Close	$91.40
Volume	685.42K
Average Volume	1.23M
P/E Ratio	--
52-Week High	$110.18
52-Week Low	$21.15
Dividend Yield	--
Earnings Date	--

Spyre Therapeutics, Inc. (SYRE) After-Hours Stock Price

Spyre Therapeutics, Inc. (SYRE) is trading at $92.98 in after-hours trading as of 2026-10-21 21:42:00, up 1.73% ($1.58) from the regular-session close of $91.40.

After-hours trading shows how investors are pricing SYRE after the regular session closes. The current after-hours price is above the regular-session close, indicating positive after-hours sentiment.

Spyre Therapeutics, Inc. (SYRE) 7-Day Stock Price Change

Over the past seven days, Spyre Therapeutics, Inc. (SYRE) moved from $85.90 to $92.97, representing a gain of 8.23% ($7.07).

The stock traded between $76.87 and $95.04 during the period. The latest price is near the upper end of the 7-day range, indicating strong upward.

The average daily volume was 1.33 million shares, down versus the previous seven-day period, indicating lower trading activity.

SYRE 52-Week Price Position

Position in Range: 80.7%

52W Low$21.15

52W High$110.18

SYRE is currently trading at $92.97, placing it 80.7% of the way from its 52-week low of $21.15 to its 52-week high of $110.18. This percentage reflects the stock's relative position within its 52-week trading range, not its valuation or future performance.

What is Spyre Therapeutics, Inc. (SYRE)?

Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Spyre Therapeutics, Inc. Information

Industry	PHARMACEUTICAL PREPARATIONS
Employees	112
Exchange	NASDAQ
Company Website	https://www.spyre.com

How to Buy Spyre Therapeutics, Inc. (SYRE) Stock on MEXC

Eligible investors can buy real shares of Spyre Therapeutics, Inc. (SYRE) through MEXC RealStocks. Follow these three steps to open a RealStocks account, transfer USDT, and place a US stock order.

Step 1: Open and Verify Your RealStocks Account

Log in to the MEXC App, go to Trade → RealStocks, and select Open Account. Complete the required account-opening and identity verification process with MEXC's partner licensed broker.

Step 2: Transfer USDT to Your RealStocks Account

Go to Wallets → RealStocks and transfer USDT from your Spot Account to your RealStocks Account. RealStocks are quoted in USD, while account funding can be completed using USDT.

Step 3: Search for SYRE and Place Your Order

Open the RealStocks trading page and search for SYRE. Select a market or limit order, enter the price and quantity as required, review the order details, and submit your order. Once filled, the corresponding real shares will be held in your RealStocks Account.

Frequently Asked Questions (FAQ)

1.What is Spyre Therapeutics, Inc. (SYRE) stock price today?

Spyre Therapeutics, Inc. (SYRE) is currently trading at $ 92.97, up 1.72% ($1.57) from the previous close of $ 91.40. Intraday prices update in real time during regular trading hours.

2.Is SYRE stock going up or down today?

As of 2026-10-21 21:42:00, SYRE is trading at $ 92.97, up 1.72% ($1.57) from its previous close of $ 91.40. The stock has traded between $ 10.42 and $ 110.18 during today’s regular session. Past price movements do not guarantee future results.

3.What is SYRE pre-market price?

As of 2026-10-21 21:42:00, SYRE is trading at $ 90.33 in pre-market trading, down 1.17% ($1.07) from the previous close of $ 91.40. Pre-market prices reflect trading activity before the regular session opens and may experience lower liquidity and higher volatility.

4.What is SYRE after-hours price?

As of 2026-10-21 21:42:00, SYRE is trading at $ 92.98 in after-hours trading, up 1.73% ($1.58) from the regular-session close of $ 91.40. After-hours prices may differ from the regular session’s opening price due to lower liquidity and wider bid-ask spreads.

5.Is SYRE stock trading now?

SYRE trades on the NASDAQ exchange during regular hours, Monday through Friday, 9:30 AM to 4:00 PM ET, excluding public holidays. Pre-market and after-hours trading are also available through select brokers outside these hours.

6.Where does SYRE sit relative to its 52-week high and low?

Over the past 52 weeks, SYRE has traded between a low of $ 21.15 and a high of $ 110.18. At $ 92.97, the stock is positioned 80.7% of the way from its 52-week low to its 52-week high, providing context for its current price within the one-year trading range.

7.What sector is Spyre Therapeutics, Inc. in?

Spyre Therapeutics, Inc. (SYRE) operates in the PHARMACEUTICAL PREPARATIONS sector. Sector classification helps investors compare it with companies exposed to similar market trends and competitive conditions.

8.What is Spyre Therapeutics, Inc.'s market capitalization and where is it listed?

Spyre Therapeutics, Inc. is listed on the NASDAQ exchange with a market capitalization of $ 7.92B. Market cap reflects the total market value of all outstanding shares and is commonly used to classify stocks by size.

9.How is SYRE valued in terms of P/E ratio and EPS?

SYRE trades at a P/E ratio of --, based on trailing-twelve-month EPS of $ -1.61. P/E ratio compares the stock price to earnings per share and is a common starting point for assessing valuation relative to peers.

10.Does Spyre Therapeutics, Inc. pay a dividend?

Spyre Therapeutics, Inc. pays an indicated annual cash dividend of $ 0.00 per share, with a current dividend yield of 0.00% based on the latest share price. Dividend policies are subject to change at the board's discretion.